Challenges in severe asthma
Significant challenges exist in severe asthma, such as persistent exacerbations, hospitalizations, and symptoms contributing to poor quality of life.2
EpiDashboard
Welcome to the EpiDashboard! Explore key learning content related to epithelial science, meet the team of experts who have co-created this platform and visit our Resource Library for downloadable content and supporting resources.
Scientific and Resource LibraryCongress highlights: ATS 2022
Read our highlights from the ATS 2022 meeting in San Francisco, including key takeaways and a summary of latest data shared.
Download highlightsAsthma heatmap
NOVEMBER 2022 UPDATE: Do you know the proportion of people with severe uncontrolled asthma in your area? Click here to view our asthma heatmap to find out more.
Open HeatmapAsthma mechanism of disease video
Watch our mechanism of disease video to find out more about the role of epithelial cytokines in the pathobiology of asthma.
Access videoEPIFUNDAMENTALS
Article
Article
Complexity of severe asthma
Overlapping and changing inflammatory pathways in response to an exacerbation, trigger, or treatment change highlight the complexity of severe asthma.1–4
Article
Role of the epithelium in asthma
The airway epithelium is the first point of contact for environmental triggers and initiates inflammation and structural changes that contribute to asthma.1–3
Epithelial cytokines (eg, TSLP) are released in response to triggers, initiating a cascade of immune responses that drive clinical features of asthma.1–4
In addition to his clinical practice and teaching, Professor Boulet’s research aims to establish links between basic research and clinical science in the field of asthma and respiratory allergy.
Professor Louis-Philippe Boulet, MD, FRCPC
Professor of Medicine, Department of Medicine, Laval University
SCIENTIFIC AND RESOURCE LIBRARY
Explore our curated library of materials to support and extend the ‘EpiFundamentals’ modules. Access latest research insights and download helpful assets to support your understanding of epithelial science. Remember to check back as the library will be updated regularly.
Slide deck summarizing the involvement of the epithelial cytokines in asthma.
Professor Porsbjerg and Professor Boulet explore how the epithelial cytokines drive airway inflammation and airway hyperresponsiveness in asthma.
The role of epithelial cytokines in asthma.
Infographic summarizing the assessment and measurement of patient experience in severe asthma.
Infographic summarizing the inflammatory pathways in asthma.
An infographic explaining the biomarkers in asthma, including their advantages and limitations.
Infographic summarizing the consequences of suboptimal asthma control.
Slide deck outlining the burden and remaining challenges in severe asthma.
Dr. Michael E. Wechsler describes the heterogeneity of severe asthma and the burden of uncontrolled disease on the lives of patients with severe asthma.
Dr. Michael E. Wechsler describes the burden of severe asthma and the spectrum of triggers, overlapping inflammatory pathways, and role of the epithelium that is associated with the complexity of severe asthma.