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Scientific and Resource Library

Congress highlights: ATS 2022

Read our highlights from the ATS 2022 meeting in San Francisco, including key takeaways and a summary of latest data shared.

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Asthma heatmap

NOVEMBER 2022 UPDATE: Do you know the proportion of people with severe uncontrolled asthma in your area? Click here to view our asthma heatmap to find out more.

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Asthma mechanism of disease video

Watch our mechanism of disease video to find out more about the role of epithelial cytokines in the pathobiology of asthma.

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Featured EpiArticle Challenges in severe asthma

Challenges in severe asthma

Significant challenges exist in severe asthma, such as persistent exacerbations, hospitalizations, and symptoms contributing to poor quality of life.2

Overlapping and changing inflammatory pathways in response to an exacerbation, trigger, or treatment change highlight the complexity of severe asthma.1–4

The airway epithelium is the first point of contact for environmental triggers and initiates inflammation and structural changes that contribute to asthma.1–3

Epithelial cytokines (eg, TSLP) are released in response to triggers, initiating a cascade of immune responses that drive clinical features of asthma.1–4

Airway hyperresponsiveness is an intricate interplay of airway inflammation, airway remodeling,1 and airway smooth muscle hypercontractility.2 


Explore our curated library of materials to support and extend the ‘EpiFundamentals’ modules. Access latest research insights and download helpful assets to support your understanding of epithelial science. Remember to check back as the library will be updated regularly.

Slide deck summarizing the involvement of the epithelial cytokines in asthma.

Professor Porsbjerg and Professor Boulet explore how the epithelial cytokines drive airway inflammation and airway hyperresponsiveness in asthma.

The role of epithelial cytokines in asthma.

Infographic summarizing the assessment and measurement of patient experience in severe asthma.

Infographic summarizing the inflammatory pathways in asthma.

An infographic explaining the biomarkers in asthma, including their advantages and limitations.

Infographic summarizing the consequences of suboptimal asthma control.

Slide deck outlining the burden and remaining challenges in severe asthma.

Dr. Michael E. Wechsler describes the heterogeneity of severe asthma and the burden of uncontrolled disease on the lives of patients with severe asthma.

Dr. Michael E. Wechsler describes the burden of severe asthma and the spectrum of triggers, overlapping inflammatory pathways, and role of the epithelium that is associated with the complexity of severe asthma.