Scientific and Resource Library

Discover more about the inflammatory pathways that contribute to upper and lower airway diseases.

An infographic highlighting the prevalence of various asthma triggers and their impact on disease burden among patients with severe asthma.

Download this slide to learn more about the inflammatory pathways in COPD.

Discover the critical role of the nasal epithelium in CRSwNP.

Download this slide deck to learn more about the role of the epithelium in different phenotypes of chronic rhinosinusitis.

Epithelial cytokines promote the release and production of downstream cytokines implicated in airway inflammation. Download this infographic to explore the role of these downstream cytokines in mucus plugging.

Listen to Professor Christopher Brightling and Professor Bruce Levy discuss the role of airway hyperresponsiveness and its importance in clinical practice.

Download this slide deck, developed in collaboration with Professor Lena Uller, to access an overview of the inflammatory pathways and cellular mechanisms that underpin severe asthma pathogenesis.

Explore this interactive pdf, co-created by Professor Ian Pavord and Assistant Professor Simon Couillard, to learn more about various milestones in asthma research and management throughout history to the present day.

Watch Professor Ian Pavord and Assistant Professor Simon Couillard discuss various key milestones in asthma research and management throughout history to the present day.

Access the Learn to Understand and Manage Severe Asthma (LUMA) educational platform to find out more information on severe asthma and uncontrolled asthma, including indicators, causes of immune response, and asthma management for patients and caregivers.

Find out more about the international guidelines from the American Thoracic Society (ATS) and European Respiratory Society (ERS) on the definition, evaluation, and treatment of severe asthma.

View the Global Initiative for Asthma (GINA) Global Strategy for Asthma Management and Prevention 2024 Report to find the latest information on asthma management.

Access the Asthma Impairment and Risk Questionnaire (AIRQ®) to assess asthma control.

Download this infographic for an overview of the role of epithelial cytokines across the multiple inflammatory pathways in severe asthma.

Slide deck summarizing the involvement of the epithelial cytokines in asthma.

Professor Christopher Brightling explores epithelial cytokines acting across the spectrum of asthma inflammation.

Download this slide deck describing the roles of airway inflammation, airway remodeling, and structural changes in airway hyperresponsiveness.

Download this slide deck outlining the different testing methods for airway hyperresponsiveness.

Download this one-page infographic summarizing the important roles TSLP and mast cells play in allergic T2 and T2-independent pathways.

Download this slide deck to access 3D image stills of our 'Mechanism of Disease' video and learn more about the central role of the epithelium in disease pathogenesis.

Need an overview of EpiCentral’s key educational content? Download this slide deck to explore highlights of the ‘EpiFundamentals’ modules and learn more about the central role of the epithelium.

Professor Michael E. Wechsler describes the heterogeneity of severe asthma and the burden of uncontrolled disease on the lives of patients with severe asthma.

Dr. Jonathan Corren describes the inflammatory pathways that underpin the complexity of inflammation in severe asthma.

Watch this video to learn more about the pathological changes that occur in the airways of people with asthma and how this manifests as clinical symptoms.

Watch this video to learn more about how TSLP interacts with mast cells in asthma, contributing to airway hyperresponsiveness.

Watch this video to learn more about the role of epithelial cytokines in asthma and their role in driving disease pathogenesis.

Watch this video to learn more about the inflammatory cascade that drives asthma pathogenesis and explore how epithelial cytokines initiate inflammation through their effects on various immune cells.

Watch this video to learn more about damage to the airway epithelium in asthma and the central role of epithelial cytokines in driving inflammatory responses.

Watch this video to journey through the airways and learn more about the role of epithelial cytokines in asthma.

Watch Professor Celeste Porsbjerg and Professor Louis-Philippe Boulet explore how the epithelial cytokines drive airway inflammation, airway hyperresponsiveness, and clinical features in asthma.

An infographic summarizing the assessment and measurement of patient experience in severe asthma.

An infographic explaining the biomarkers in asthma, including their advantages and limitations.

Watch Professor Michael E. Wechsler describe the burden of severe asthma and the spectrum of triggers, overlapping inflammatory pathways, and role of the epithelium that is associated with the complexity of severe asthma.

Learn more about the science behind how TSLP correlates with clinical features of asthma.